A Novel Therapy Ameliorates Obesity and Type 2 Diabetes in Mice Fed a High-Fat Diet: This Therapy, Using Sustained Release of Nitric Oxide, May Be a Novel, Efficient and Safe Way to Prevent and Treat
A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing the inner muscles of blood vessels. "Because reduced bioavailability of nitric oxide is the hallmark of cardiometabolic syndrome, supplying exogenous nitric oxide at a sustained level may be an efficient way of treating the cardiometabolic syndrome," said Jeonga Kim, Ph.D., leader of the UAB study.